Bosentan

Bosentan

Bosentan

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Product Details

A mixed endothelin receptor antagonist. Used as a vasodilator. Antihypertensive.

CAS:147536-97-8


Appearance

White or light yellow powder

Solubility

Soluble   in dimethylformamide and acetonitrile, insoluble in water

Identification

IR spectrum corresponds to the IR spectrum of the   reference standard

Heavy metals

NMT 10ppm

Impurities

Impurity E

NMT 0.15%

Impurity D

NMT 0.15%

Impurity B

NMT 0.15%

Impurity A

NMT 0.15%

Impurity C

NMT 0.15%

Any individual unknown impurity

NMT0.05%

Total impurities

NMT0.3%

Water

2.0%~4.0%

Residue on ignition

NMT 0.1%

Limit   of Ethylene glycol

NMT 620ppm

Microbial limits

Total bacterial count NMT 100CFU; Yeast &   Mold NMT 100CFU;

e . coli should be not detected

Assay

98.0%~102.0%

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