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White Powder Meglumine Amidotrizoate Sodium Amidotrizoate Meglumine GMP

Minimum Order Quantity : 1KG Price : to be negotiated
Packaging Details : 30KG/DRUM Delivery Time : PROMPT, 30days
Payment Terms : T/T Supply Ability : 1MT/MONTH
Place of Origin: CHINA Brand Name: LIBANG
Model Number: USP

Detail Information

COLOR: WHITE Documents: COA, MSDS
Pack: 25kg/drum Batch Size: 500kg
Pack Material: Allumium Foil Bag Pack Materials: Fiber Drum
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White Powder Meglumine Amidotrizoate

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Meglumine Amidotrizoate Sodium Amidotrizoate powder

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Amidotrizoate Meglumine GMP

Product Description

Sodium Diatrizoate white powder with slight odour USP in China GMP

 

Diatrizoic acid may be used as an alternative to barium sulfate for medical imaging of the gastrointestinal tract, such as upper gastrointestinal series and small bowel series. It is indicated for use in patients who are allergic to barium, or in cases where the barium might leak into the abdominal cavity. It does not coat the stomach/bowel lining as well as barium, so it is not used commonly for this purpose.[citation needed]

It is also used to treat Ascaris lumbricoides (roundworms). Diatrizoate may not actually kill Ascaris, but instead it promotes shifting of fluid in the bowel lumen[clarify], so may relieve intestinal obstruction caused by impacted Ascaris.

Diatrizoate is used in suspected intestinal perforation, meconium ileus, and to identify bowel-lumen communication. It should not be used to investigate tracheo-oesophageal fistula because it can cause pulmonary oedema when aspirated into respiratory system. Diatrizoate can dislodge sticky meconium by drawing water into intestines. Diatrizoate is minimally absorbed from the intestines and excreted into urinary bladder. Because of its high osmolarity it can draw water from the surrounding tissues into the intestines, thus cause dehydration in people with already small plasma volume such as infants. Because of the additives and flavouring agents, diatrizoate must not be used intravascularly. This chemical must be keep away from sunlight during storage.

Synonym: Amidotrizoic acid; Diatrizoate

Chemical Name: Benzoic acid, 3,5-bis(acetylamino)-2,4,6-triiodo-, dihydrate

CAS: 50978-11-5; 117-96-4 (anhydrous) RTECS Number: DG5950000 (anhydrous)

Chemical Family: 2,4,6 - Triiodo derivative

Therapeutic Category: Diagnostic aid (radiopaque medium)

Composition: Pure Material

Manufacturer: Xian Libang Pharmaceutical Co., Ltd.

Mailing Address: West door Outside, Guo Town, Chencang District, Baoji City, China

TEST SPECIFICATION RESULT
Appearance White, odorless powder Conforms
Identification (1) It responds to the Thin-Layer Chromatographic Identification Test Conforms
(2) Positive reaction Conforms
Water 4.5%~7.0% 5.6%
Residue on ignition NMT0.1% 0.06%
Iodine and iodide NMT 0.02% of iodide

 

Conforms

Heavy metals NMT 0.002% Conforms
Free aromatic amine NMT 0.05% 0.008%
Ethyl alcohol NMT 0.5% Not detected
Acetic acid NMT 0.5% Not detected
Bacterial endotoxins NMT 1.5 EU/g <1.5 EU/g
Microbial Limit Total aerobic microbial count: <1000 cfu/g Conforms
Total yeast and molds count: <100 cfu/g Conforms
Assay 98.0%~102.0%(Calculated on the anhydrous basis) 99.2%
 

 

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