
Diatrizoic Acid For Medical Imaging Soluble In Water And Alcohol
Contact Person : Jimmy Tian
Phone Number : 86-18602905046
WhatsApp : +8618602905046
Detail Information |
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COLOR: | WHITE | Documents: | COA, MSDS |
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Pack: | 25kg/drum | Batch Size: | 500kg |
Pack Material: | Allumium Foil Bag | Pack Materials: | Fiber Drum |
Highlight: | White Powder Meglumine Amidotrizoate,Meglumine Amidotrizoate Sodium Amidotrizoate powder,Amidotrizoate Meglumine GMP |
Product Description
Diatrizoic acid may be used as an alternative to barium sulfate for medical imaging of the gastrointestinal tract, such as upper gastrointestinal series and small bowel series. It is indicated for use in patients who are allergic to barium, or in cases where the barium might leak into the abdominal cavity. It does not coat the stomach/bowel lining as well as barium, so it is not used commonly for this purpose.[citation needed]
It is also used to treat Ascaris lumbricoides (roundworms). Diatrizoate may not actually kill Ascaris, but instead it promotes shifting of fluid in the bowel lumen[clarify], so may relieve intestinal obstruction caused by impacted Ascaris.
Diatrizoate is used in suspected intestinal perforation, meconium ileus, and to identify bowel-lumen communication. It should not be used to investigate tracheo-oesophageal fistula because it can cause pulmonary oedema when aspirated into respiratory system. Diatrizoate can dislodge sticky meconium by drawing water into intestines. Diatrizoate is minimally absorbed from the intestines and excreted into urinary bladder. Because of its high osmolarity it can draw water from the surrounding tissues into the intestines, thus cause dehydration in people with already small plasma volume such as infants. Because of the additives and flavouring agents, diatrizoate must not be used intravascularly. This chemical must be keep away from sunlight during storage.
Chemical Name: Benzoic acid, 3,5-bis(acetylamino)-2,4,6-triiodo-, dihydrate
CAS: 50978-11-5; 117-96-4 (anhydrous) RTECS Number: DG5950000 (anhydrous)
Chemical Family: 2,4,6 - Triiodo derivative
Therapeutic Category: Diagnostic aid (radiopaque medium)
Composition: Pure Material
Manufacturer: Xian Libang Pharmaceutical Co., Ltd.
Mailing Address: West door Outside, Guo Town, Chencang District, Baoji City, China
TEST | SPECIFICATION | RESULT |
Appearance | White, odorless powder | Conforms |
Identification | (1) It responds to the Thin-Layer Chromatographic Identification Test | Conforms |
(2) Positive reaction | Conforms | |
Water | 4.5%~7.0% | 5.6% |
Residue on ignition | NMT0.1% | 0.06% |
Iodine and iodide | NMT 0.02% of iodide |
Conforms |
Heavy metals | NMT 0.002% | Conforms |
Free aromatic amine | NMT 0.05% | 0.008% |
Ethyl alcohol | NMT 0.5% | Not detected |
Acetic acid | NMT 0.5% | Not detected |
Bacterial endotoxins | NMT 1.5 EU/g | <1.5 EU/g |
Microbial Limit | Total aerobic microbial count: <1000 cfu/g | Conforms |
Total yeast and molds count: <100 cfu/g | Conforms | |
Assay | 98.0%~102.0%(Calculated on the anhydrous basis) | 99.2% |
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