Steroidal Anti Fulvestrant Anti Cancer Drug WC Avai 129453-61-8
Contact Person : Jimmy Tian
Phone Number : 86-18602905046
WhatsApp : +8618602905046
Minimum Order Quantity : | 50g | Price : | to be negotiated |
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Packaging Details : | Inner package: double PE bag. Out package: 1-3kg in a Aluminum Tin | Delivery Time : | 20 days |
Payment Terms : | T/T, L/C | Supply Ability : | 15 kg one month |
Place of Origin: | China | Brand Name: | LIBANG |
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Certification: | Chinese GMP and Written Confirmation for Exporting to EU |
Detail Information |
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Pharmacological Class: | Receptor Antagonists | Delivery: | 20 Working Days |
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Batch Size: | 2.5 Kg | Storage: | Store At 2~8℃ |
Certi: | WC | Pack: | Double PE Bag |
High Light: | GMP Fulvestrant Powder,Fulvestrant Powder WC,WC Receptor Antagonists |
Product Description
Fulvestrant CAS No.129453-61-8 Anti-Cancer Drug Substance
Fulvestrant is a steroidal anti that is used in the treatment of hormone-receptor positive metastatic breast cancer.
Fulvestrant, sold under the brand name Faslodex among others, is a medication used to treat hormone receptor (HR)-positive metastatic breast cancer in postmenopausal women with disease progression as well as HR-positive, HER2-negative advanced breast cancer in combination with palbociclib in women with disease progression after endocrine therapy. It is given by injection into a muscle.
Fulvestrant is a selective receptor degrader (SERD) and was first-in-class to be approved. It works by binding to the receptor and destabilizing it, causing the cell's normal protein degradation processes to destroy it.
TEST | SPECIFICATION | |
Character | White powder,freely soluble in alcohol(95%). | |
Foreign Matter-IH |
The sample should be essentially free from black particles and foreign matter that can be observed on visual inspection. |
|
Identification A: IR | Consistent with spectrum of standard reference. | |
Identification B:
|
The retention time of the major peak in the chromatogram of the assay preaparation corresponds to that of the standard preparation. | |
Water | Not more than 0.5% | |
Related Compounds | ||
6-Keto-fulvestrant | Not more than 0.10% | |
Δ6,7-Fulvestrant | Not more than 0.10% | |
Fulvestrant sulfone | Not more than 0.15% | |
Fulvestrant extended | Not more than 0.15% | |
Fulvestrant sterol dimer | Not more than 0.15% | |
Any individual unspecified maximum impurity |
Not more than 0.10% | |
Total Impurities | Not more than 1.0% | |
Ratio of Isomers | ||
Fulvestrant A | 42.0%-48.0% | |
Fulvestrant B | 52.0%-58.0% | |
Residue of Solvents | ||
Tetrahydrofuran | Not more than 720ppm | |
Ethyl Acetate | Not more than 5000ppm | |
Dichloromethane | Not more than 600ppm | |
n-hexane | Not more than 290ppm | |
Ethanol | Not more than 5000ppm | |
Acetic acid
|
Not more than 5000ppm | |
Ethyl
|
Not more than 5000ppm | |
Heavy metals | Not more than 0.001% | |
Residue on ignition | Not more than 0.1% | |
Specific rotation | 108-115 at 365nm | |
Assay | 98%~102.0% |
Xi'an Libang Pharmaceutical Co..Ltd developed Fulvestrant API since 2007 and filed the DMF in US FDA in 2009.
Xi'an Libang Pharmaceutical Co., Ltd. was established in 1996, It is a professional Manufacture specializing in pharmaceutical raw materials and Finished dosage form. The company has gathered a dedicated and professional sales and technical personnel. We have a marketing team with first-class efficiency and first-class service! Strong technical force, high quality and low price products, first-class marketing and after-sales service are your best choice!
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