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FDF Propofol 20ml Injectable Emulsion 2078-54-8 Surgical

Minimum Order Quantity : 20,000amps Price : to be negotiated
Packaging Details : 5amps/box, 40boxes /carton Delivery Time : propmt after payment done
Payment Terms : T/T, L/C Supply Ability : 100,000 Amps/month
Place of Origin: China Brand Name: LIBANG
Certification: Chinese GMP

Detail Information

Colour: White, Aqueous And Isotonic Emulsion Batch Size: Approx 50000 Amps
Pack: 5amps/box Storage: Stored At 2-25 OC
Delivery: 30 Working Days After Packing CFMD Stock: 200,000amps In Chinese Pack
High Light:

FDF Propofol

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Propofol 20ml Injectable Emulsion

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2078-54-8 Surgical

Product Description

                                                      Propofol Injectable Emulsion Agent

Xi'an Libang Pharmaceutical Co., Ltd. was established in 1996, It is a professional Manufacture specializing in pharmaceutical raw materials and Finished dosage form. The company has gathered a dedicated and professional sales and technical personnel. We have a marketing team with first-class efficiency and first-class service! Strong technical force, high quality and low price products, first-class marketing and after-sales service are your best choice!

Propofol is a well-known agent,  Xi'an Libang Pharmaceutical Co..Ltd developed and lauched firstly Prpofol API in China since 1996. 

 

Anesthesia
To induce general anesthesia, propofol is the drug used almost exclusively, having largely replaced sodium thiopental. It can also be administered as part of an anesthesia maintenance technique called total intravenous anesthesia, using either manually programmed infusion pumps or computer-controlled infusion pumps in a process called target controlled infusion (TCI). Propofol is also used to sedate individuals who are receiving mechanical ventilation but not undergoing surgery, such as patients in the intensive care unit. In critically ill patients, propofol is superior to both in effectiveness and overall cost. Propofol is relatively inexpensive compared to medications of similar use due to shorter ICU stay length. One of the reasons propofol is thought to be more effective (although it has a longer half-life than ) is because studies have found that like and tend to accumulate in critically ill patients, prolonging sedation. Propofol has also been suggested as a sleep aid in critically ill adults in the ICU; however, the effectiveness of this medicine at replicating the mental and physical aspects of sleep for people in the ICU is not clear.
Propofol can be run through a peripheral IV or central line. Propofol is frequently paired with (for pain relief) in intubated and sedated people. The two drugs are compatible in IV form.

Propofol is also used for deepening of anesthesia in order to relieve laryngospasm. It may be used alone or followed by succinylcholine. Its use can avoid the need for paralysis and in some instances the potential side-effects of succinylcholine.

Test Item Specification Result
Appearance White, aqueous and isotonic emulsion. Conforms
Identification (1) UV Maximum absorption at 272 nm. Corresponds
Identification (2) HPLC The retention time of the major peak corresponds to that of the standard solution. Corresponds
pH Value 6.0~8.5 8.2

Globule size

distribution

MDD should be less than 0.5μm. Conforms
PFAT5 should not exceed 0.05%. Conforms
Free Fatty Acids The consumed sodium hydroxide TS (0.01mol/L) should be not more than that consumed in the reference solution. Conforms
Peroxide value The consumed Na2S2O3 VS (0.01mol/L) should be NMT 1.0 ml. Conforms
Related compounds Impurity I NMT 0.1% Not detected
Impurity II NMT 0.5% Not detected
Other impurities (Individual) NMT 0.2% Not detected
Other impurities (Total) NMT 0.4% Not detected
Anisidine NMT 5.0 1.3
LPC NMT 2.0mg/mL 0.40mg/mL
LPE NMT0.6mg/mL Conforms
Glycerol 20.2~24.8mg 23.2mg/mL
Phosphorus 0.400.50mg/mL 0.47mg/mL
Osmolality 280~330mOsmol/kg 311mOsmol/kg
Bacterial endotoxins Less than 0.33EU/mg Conforms
Sterility test No evidence of microbial growth Sterile
Others

It meets the requirements in Injections (Appendix I B)

 

Conforms
Assay 95.0%~105.0% 100.8%
 

 

 

FDF  Propofol 20ml Injectable Emulsion 2078-54-8 Surgical  0

 

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